LighterLife research
LighterLife is currently sponsoring
research in conjunction with Professor John Iain Broom at
Robert Gordon University in Aberdeen. The study is a randomised
controlled trial comparing the effectiveness of a healthy eating,
calorie-deficient diet versus a very-low-calorie diet (VLCD) or a
low-carbohydrate/high-protein diet (LCHP).
The first published data from the trial show
that greater weight loss and improved cardiovascular risk were
achieved with the LighterLife Total VLCD compared with LCHP and the
healthy eating, calorie-deficient diet.
More details
here.
LighterLife is also running community-based
studies in partnership with the NHS.
LighterLife places a high priority on
evidence-based practice and regularly presents research about its
weight-loss and weight-management programmes at national, European
and international obesity conferences.
RCGP Annual Primary Care Conference,
Liverpool, October 2011
Ketosis, ketoacidosis
and very-low-calorie diets: putting the record straight
Mullins G, Hallam C, Broom J.
Very-low-calorie diets (VLCDs) are used to treat obesity, often
in a non-clinical setting, and the typical formulation of a minimum
of 50 g carbohydrates daily can induce a mild dietary ketosis. This
clinically benign state is sometimes confused with the
non-metabolically adapted state of ketoacidosis, and this
misunderstanding may lead to the rejection of VLCDs as a suitable
obesity treatment. This paper summarises and discusses the
difference between physiological ketosis and pathological
ketoacidosis, the benefits of ketosis-inducing weight-loss regimen
such as VLCDs and why ketoacidosis should never be the diagnosis in
a non-type 1 diabetic on a carbohydrate-restricted diet.
Heart UK 25th Annual Conference, July
2011
Partners in Prevention - Lipids in Cardiovascular Disease and
Beyond
Poster
presentations by LighterLife at the 18th European Congress on
Obesity (ECO), Istanbul, Turkey 2011
- Hallam C et al. Mean weight loss
achieved in 12 weeks by 4374 obese female patients on the
LighterLife Total VLCD weight-loss programme in 2010. Obesity
Reviews 2011
- Hallam C et al. Mean weight loss achieved
in 8 weeks by 1006 obese male patients on the LighterLife Total
VLCD weight-loss programme in 2010. Obesity Reviews 2011
- Hallam C et al. Mean weight loss
results for 2007 overweight female patients following 8 weeks of
the LighterLife Lite LCD weight-loss programme in 2010. Obesity
Reviews 2011
- Hallam C et al. Year-on-year
comparison of male and female patients following 12 weeks of the
LighterLife Total VLCD weight-loss programme. Obesity Reviews
2011
- Hallam C et al. Reporting on
1-year outcome for weight maintenance in a cohort of 4915 patients
after a mean weight loss of 23.4kg on the LighterLife Total VLCD.
Obesity Reviews 2011
- Hallam C et al. Reporting on
2-year outcome for weight maintenance in a cohort of 787 patients
after a mean weight loss of 24.5kg (3st 12lb) on the LighterLife
Total VLCD. Obesity Reviews 2011
- Hallam C et al. Reporting on
3-year outcome for weight maintenance in a cohort of 179 patients
after a mean weight loss of 24.3kg (3st 12lb) on the LighterLife
Total VLCD. Obesity Reviews 2011
- Cassidy M et al. Is psychology
more important than environment in over-consuming behaviours? An
interim report. Obesity Reviews 2011
- Cassidy M et al. 4-week vs.
12-week closed group approach in the treatment of obesity with the
LighterLife Total VLCD achieved greater weight loss, contrary to
group-dynamics theories. Obesity Reviews 2011
- Hallam C et al. Evaluation of
LighterLife Total VLCD programme run in an NHS GP practice to
provide weight-loss treatment for obese patients with BMI ≥37.
Obesity Reviews 2011
- Hallam C et al. The importance of
robust screening for suitability in those wishing to participate in
a VLCD. Obesity Reviews 2011
European
Congress on Obesity (ECO) 2009
- Effects of a
low-carbohydrate and a very-low-calorie diet on hepatic and renal
function.
Rolland C, Hession M, Murray S, Salsbury J, Wise A, Broom J.
- Effects of a
low-carbohydrate and a very-low-calorie diet on overall quality of
life.
Rolland C, Hession M, Murray S, Wise A, Broom J.
European Congress on Obesity (ECO)
2008
- Baseline differences between
achievers and non achievers of weight loss in a 3 month period with
a healthy eating weight loss regimen.
Rolland C, Hession M, John O, Murray S, Wise A, Broom J.
- Comparison of kidney and liver
changes after 3 months of a low carbohydrate vs. a very low calorie
diet.
Hession, M, Rolland, C, John, O, Murray, S, Wise, A, Broom,
J.
- A randomized controlled trial of
a low-carbohydrate vs. a very low calorie diet.
Rolland C, Hession M, John O, Murray S, Wise A, Broom J.
Annual World Congress
on Insulin Resistance (WCIRS) 2008
- The response of patients with and without metabolic syndrome to
3 months of a healthy eating dietary intervention.
Rolland C, Hession M, John O, Murray S, Wise A, Broom J.
North American
Association for the Study of Obesity (NAASO) 2008
- Randomised clinical trial of
standard dietary treatment versus protein-sparing modified fast or
the LighterLife Programme in the management of obesity.
Catherine Rolland, Michelle Hession, Susan Murray, Alan Wise, Iain
Broom. Aberdeen, United Kingdom.
European
Congress on Obesity (ECO) 2007
- Occurrence and diagnosis of Type II Diabetes
in an obese population.
Rolland C, Hession M, Oomen J, Murray S, Wise A, Broom J.
Annual World Congress
on Insulin Resistance (WCIRS) 2007
- Analysis of insulin sensitivity in response to weight loss in
obese patients.
Rolland C, Stewart A, Hession M, John O, Murray S, Broom J.
International Congress
on Obesity (ICO) 2006
- Phenotypic presentation of an
obese population and their response to a healthy eating energy
deficient diet.
Rolland C, Hession M, Tuya C, Murray S, Wise A, Broom J.
- The effects of a randomised
control trial of low fat and high protein diets on cardiovascular
risk of morbidly obese patients.
Rolland C, Hession M, Tuya C, Murray S, Wise A, Broom J.
- Physical activity, general health
and depression analysis in relation to weight change after 3 months
of a healthy eating dietary intervention.
Hession M, Rolland C, Wise A, Tuya C, Murray S, Broom J.
- Weight, physical activity, and
general health changes after 3 and 6 months of dietary
interventions.
Hession M, Rolland C, Tuya C,Wise A, Murray S, Pirie I, Broom
J.
Nutrition Society
2006
- Reported weight loss from a 1 yr randomised
controlled trial examining 3 dietary interventions for obesity
management – Initial findings.
By C Rolland, M Hession, C Tuya, S Murray, K Jarrett, A Wise and J
Broom.
European
Congress on Obesity (ECO) 2005
- The role of the LighterLife
weight loss programme in lowering the cost of obesity.
A Wise, C Rolland, J Cox, BH Hewlett, M Hession, I Broom.
- Systematic review of randomized
controlled trials of low-carbohydrate vs. low-fat/low-calorie diets
in the management of obesity and its comorbidities.
Hession M, Rolland C, Kulkarni U, Wise A, Broom J.
Centre for Obesity Research and Epidemiology (CORE), Faculty of
Heath and Social Care, Robert Gordon University, Aberdeen, UK.
Poster
presentations by LighterLife at the 11th International Congress on
Obesity (ICO), Stockholm, Sweden 2010
- Hallam CL et al. Reporting on 3-year
outcome for weight maintenance in a cohort of 60 patients after a
mean weight loss of 21.6kg (3st 5lb) on the LighterLife Total VLCD.
Obesity Reviews 2010, Volume 11 Supplement 1;241.
- Hallam CL et al. Reporting on 2-year
outcome for weight maintenance in a cohort of 502 patients after a
mean weight loss of 24.8kg (3st 13lb) on the LighterLife Total
VLCD. Obesity Reviews 2010, Volume 11 Supplement 1;241.
- Hallam CL et al. To report on 12 patients
with BMI≥50 who achieved a non-obese BMI with the LighterLife Total
VLCD weight-loss programme in 2009; a retrospective study. Obesity
Reviews 2010, Volume 11 Supplement 1;242.
- Hallam CL et al. Can a VLCD be a realistic
alternative to bariatric surgery for the super-morbidly obese? A
retrospective study of 650 patients with BMI≥50 participating in
the LighterLife Total VLCD for 12 weeks in 2009. Obesity Reviews
2010, Volume 11 Supplement 1;242.
- Hallam CL et al. To report on the weight
loss achieved in 12 weeks by 432 super-morbidly obese patients on
the LighterLife Total VLCD weight-loss programme in 2009; a
retrospective study. Obesity Reviews 2010, Volume 11 Supplement
1;243.
- Hallam CL et al. Is weight stabilisation
successful with the LighterLife weight-maintenance programme
post-VLCD? A retrospective study of 237 female patients after an
average 29.2kg (4st 8lb) weight loss on the LighterLife Total VLCD.
Obesity Reviews 2010, Volume 11 Supplement 1;243.
- Hallam CL et al. To report on the weight
loss achieved in 12 weeks by 4306 obese female patients on the
LighterLife Total VLCD weight-loss programme in 2009; a
retrospective study. Obesity Reviews 2010, Volume 11 Supplement
1;243.
- Hallam CL et al. To report on the weight
loss achieved in 8 weeks by 1810 female patients with BMI 25-29.9
on the LighterLife Lite LCD weight-loss programme in 2009; a
retrospective study. Obesity Reviews 2010, Volume 11 Supplement
1;244.
- Hallam CL et al. To report on the weight
loss achieved in 8 weeks by 950 male patients on the LighterLife
Total for Men VLCD weight-loss programme in 2009; a retrospective
study. Obesity Reviews 2010, Volume 11 Supplement 1;244.
Poster
presentations by LighterLife at the 17th European Congress on
Obesity, Amsterdam 2009
- Salsbury J et al. Weight-loss
results for 7215 female patients with a BMI>29kg/m2
following 12 weeks on the LighterLife Programme in 2008.
International Journal of Obesity 2009; 2(suppl 2):245. Poster
presented at 17th European Congress on Obesity, Amsterdam, May
2009.
- Salsbury J et al. Weight-loss
results for 2200 male patients with a BMI>29kg/m2
following the LighterLife Programme in 2008. International Journal
of Obesity 2009; 2(suppl 2):246. Poster presented at 17th European
Congress on Obesity, Amsterdam, May 2009.
- Salsbury J et al. Two-year
outcome for weight maintenance following a cohort of 134 patients
who lost weight on the LighterLife Programme. International Journal
of Obesity 2009; 2(suppl 2):242. Poster presented at 17th European
Congress on Obesity, Amsterdam, May 2009.
- Salsbury J et al. Reduction in
mean systolic/diastolic blood pressure following 12 weeks on the
LighterLife Programme for a cohort of patients n=200. International
Journal of Obesity 2009; 2(suppl 2):243. Poster presented at 17th
European Congress on Obesity, Amsterdam, May 2009.
- Salsbury J et al. Reduction in
waist circumference following 12 weeks on the LighterLife Programme
for a cohort of patients n=180. International Journal of Obesity
2009; 2(suppl 2):244. Poster presented at 17th European Congress on
Obesity, Amsterdam, May 2009.
Poster
presentations by LighterLife at the 16th European Congress on
Obesity, Geneva 2008
- Hallam Spencer CL et al. Weight-loss
results for 1000 males following a male-specific weight management
programme in 2007. International Journal of Obesity 2008 May; 32,
S1:178. Poster presented at 16th European Congress on Obesity,
Geneva, May 2008.
- Hallam Spencer CL et al. Weight-loss
results for 5000 women following the LighterLife Programme in 2007.
International Journal of Obesity 2008 May; 32, S1:178. Poster
presented at 16th European Congress on Obesity, Geneva, May
2008.
- Holt J et al. Two-year outcome for a cohort
of 40 patients following the long-term weight-maintenance element
of the LighterLife Programme. International Journal of Obesity 2008
May; 32, S1:176. Poster presented at 16th European Congress on
Obesity, Geneva, May 2008.
- Mullins G et al. LighterLife clients'
self-reported ratings of general health and wellbeing: frequency of
tiredness. International Journal of Obesity 2008 May; 32, S1:179.
Poster presented at 16th European Congress on Obesity, Geneva, May
2008.
- Mullins G et al. LighterLife patients'
self-reported ratings of general health and wellbeing: ease of
climbing stairs. International Journal of Obesity 2008 May; 32,
S1:179. Poster presented at 16th European Congress on Obesity,
Geneva, May 2008.
- Mullins G et al. LighterLife patients'
self-reported ratings of general health and wellbeing: ease of
walking one mile. International Journal of Obesity 2008 May; 32,
S1:178. Poster presented at 16th European Congress on Obesity,
Geneva, May 2008.
Poster
presentations by LighterLife at the 15th European Congress on
Obesity, Budapest 2007
- Holt J et al. What motivates men to lose
weight? International Journal of Obesity 2007
May; 31, S1:169. Poster presented at 15th European
Congress on Obesity, Budapest, April 2007.
- Holt J et al. One year follow up of 100
post obese patients following the maintenance element of the
LighterLife Programme. International Journal of Obesity 2007
May; 31, S1:173. Poster presented at 15th European
Congress on Obesity, Budapest, April 2007.
- Holt J et al. Reporting on the mean weight
loss and reduction in BMI for 11511 females who completed 14 weeks
on the LighterLife Programme between 1998 and 2005. International
Journal of Obesity 2007 May; 31, S1:172. Poster presented
at 15th European Congress on Obesity, Budapest, April
2007.
- Holt J et al. Weight loss results for 4881
females who started the LighterLife Programme in 2005 and who
completed at least 12 weeks. International Journal of Obesity 2007
May; 31, S1:168. Poster presented at 15th European
Congress on Obesity, Budapest, April 2007.
- Holt J et al. Obese men are at higher
risk than obese women. Following a small trial, a long term
observational study will report over the next 10 years on weight
loss and weight maintenance on a group of self-referred obese
men. International Journal of Obesity 2007
May; 31, S1:169. Poster presented at 15th European
Congress on Obesity, Budapest, April 2007.